COS Development Guidance

Guidance on how to develop a core outcome set for skin disease by the CS-COUSIN methods group

  Domain Development

COS Domain Development Protocol

CS-COUSIN COS Domain Development Process

  Measure Selection/Development

CS-COUSIN COS Outcome Measurement Instrument Selection/Development Process

  COS Group Proposal Form

C3 COS Group Proposal Form

HOME Roadmap

The Harmonising Outcomes for Eczema (HOME) roadmap: A methodological framework to develop core sets of outcome measurements in dermatology. Schmitt J, Apfelbacher C, Spuls PI, Thomas KS, Simpson EL, Furue M, Chalmers J, Williams HC. J Invest Dermatol. Jan 2015;135(1):24-30. doi:10.1038/jid.2014.320

CS-COUSIN position paper

Controversy and debate on core outcome sets. Paper 6: improving the generalizability, credibility, and implementation of the core outcome sets-The example of the Cochrane Skin-Core Outcome Set Initiative. Schmitt J, Kottner J, Lange T. Journal of clinical epidemiology. May 13 2020;125, 229-231. doi:10.1016/j.jclinepi.2020.05.016

Navigating the landscape of core outcome set development in dermatology. Prinsen CA, Spuls PI, Kottner J, Thomas K, Apfelbacher C, Chalmers J, Deckert S, Furue M, Gerbens L, Kirkham J, Simpson E, Alam M, Balzer K, Beeckman D, Eleftheriadou V, Ezzedine K, Horbach SE, Ingram JR, Layton A, Weller K, Wild T, Wolkerstorfer A, Williams H, Schmitt J. J Am Acad Dermatol. Mar 13 2019;81(1), 297-305. doi:10.1016/j.jaad.2019.03.009

CS-COUSIN methods group paper

Outcome assessment in dermatology clinical trials and cochrane reviews: call for a dermatology-specific outcome taxonomy.
Lange T, Kottner J, Weberschock T, Hahnel E, Apfelbacher C, Brandstetter S, Dreher A, Datzmann T, Burden-Teh E, Rogers N, Spuls P, Grainge M, Jacobi L, Williams H, Schmitt J. J Eur Acad Dermatol Venereol. Aug 11 2020;35(2), 523-535. doi:10.1111/jdv.16854

Cochrane reviews and dermatological trials outcome concordance; why Core Outcome Sets could make trial results more usable.
Schmitt, J, Lange, T, Kottner, J, Prinsen, CAC, Weberschock, T, Hahnel, E, Apfelbacher, C, Brandstetter, S, Dreher, A, Stevens, G, Burden-Teh, E, Rogers, N, Spuls, P, Grainge, MJ, Williams, HC & Jacobi, L. J Invest Dermatol. May 2019;139(5):1045-1053. doi:10.1016/j.jid.2018.11.019

Useful links

A document about issues to consider when preparing and conducting online consensus meetings has been published by the COMET initiative: