Disease State: Appearance of Facial Aging
Background
While aging is not a disease, the physical manifestations of facial aging are often considered as a group, with constituent elements including the visible signs of chronological and photoaging, body image effects, and social impact. As an unwanted condition, facial aging and its manifestations are often treated in an attempt to restore some features of more youthful skin. Treatment interventions may include topical agents, injectables, laser and energy procedures, cosmetic surgeries, or other treatments. Since the appearance of facial aging is a category in common use, there is a need for a specific core outcome set to measure treatment-associated changes.
Project Goal
We aim to develop a core outcome set by (1) identifying all current outcomes from a systematic review of literature; (2) involving other stakeholder groups such as other clinicians, and regulators to participate in identifying additional outcomes; (3) conducting Delphi consensus exercises on the identified outcomes; (4) presenting all results from the Delphi exercises during a face-to-face (if possible) consensus meeting to vote and agree upon a core set of outcomes important for cosmetic aging research.
Project Lead
Murad Alam
Key Project Team Members
Steering Committee
Murad Alam
Joseph Sobanko
Ian Maher
Todd V. Cartee
C3 Methods Partner
Jamie Kirkham
Contact
Murad Alam (m-alam@northwestern.edu)
Publications
- Schlessinger DI, Iyengar S, Yanes AF, Henley JK, Ashchyan HJ, Kurta AO, Patel PM, Sheikh UA, Franklin MJ, Hanna CC, Chen BR, Chiren SG, Schmitt J, Deckert S, Furlan KC, Poon E, Maher IA, Cartee TV, Sobanko JF, Alam M. Development of a core outcome set for clinical trials in facial aging: study protocol for a systematic review of the literature and identification of a core outcome set using a Delphi survey. Trials. 2017;18(1):359. https://pubmed.ncbi.nlm.nih.gov/28764734/
Updated on May 1, 2022